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DeCS
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Descriptor English:
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1-Alkyl-2-acetylglycerophosphocholine Esterase
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Descriptor Spanish:
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1-Alquil-2-acetilglicerofosfocolina Esterasa
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Descriptor Portuguese:
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1-Alquil-2-acetilglicerofosfocolina Esterase
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Synonyms English:
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PAF Acetylhydrolase
Platelet-Activating Factor Hydrolase
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Tree Number:
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D08.811.277.352.100.680.750.937.249
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Definition English:
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A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA. |
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History Note English:
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2004(1983)
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Allowable Qualifiers English:
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Record Number:
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38141
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Unique Identifier:
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D043203
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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